Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke

Ischemic stroke is the second leading cause of death worldwide. Following an ischemic event, neuronal death is triggered by uncontrolled glutamate release leading to overactivation of glutamate sensitive N-methyl-d-aspartate receptor (NMDAR). For gating, NMDARs require not only the binding of glutam...

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Detalles Bibliográficos
Autores principales: Cappelli, Julia, Khacho, Pamela, Wang, Boyang, Sokolovski, Alexandra, Bakkar, Wafae, Raymond, Sophie, Ahlskog, Nina, Pitney, Julian, Wu, Junzheng, Chudalayandi, Prakash, Wong, Adrian Y.C., Bergeron, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689229/
https://www.ncbi.nlm.nih.gov/pubmed/34977503
http://dx.doi.org/10.1016/j.isci.2021.103539

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