Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance

OBJECTIVE: The contribution of beta-cell dysfunction to type 2 diabetes (T2D) is not restricted to insulinopenia in the late stages of the disease. Elevated fasting insulinemia in normoglycemic humans is a major factor predicting the onset of insulin resistance and T2D, demonstrating an early altera...

Descripción completa

Detalles Bibliográficos
Autores principales: Shum, Michael, Segawa, Mayuko, Gharakhanian, Raffi, Viñuela, Ana, Wortham, Matthew, Baghdasarian, Siyouneh, Wolf, Dane M., Sereda, Samuel B., Nocito, Laura, Stiles, Linsey, Zhou, Zhiqiang, Gutierrez, Vincent, Sander, Maike, Shirihai, Orian S., Liesa, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689243/
https://www.ncbi.nlm.nih.gov/pubmed/34823065
http://dx.doi.org/10.1016/j.molmet.2021.101403

Ejemplares similares

Ejemplares similares