The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer

AIM: Evaluate impact of lymph node ratio as prognostic factor in gastric cancer. METHODS: We studied 463 patients with gastric cancer who underwent curative gastric surgery with D1 or D2 lymphadenectomy, Data were collected from May 1996 through December 2010 at Department of General Surgery of Parm...

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Detalles Bibliográficos
Autores principales: Giuffrida, Mario, Viani, Lorenzo, Iapichino, Gioacchino Giovanni, Cozzani, Federico, Dell’Abate, Paolo, Del Rio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689297/
https://www.ncbi.nlm.nih.gov/pubmed/34738601
http://dx.doi.org/10.23750/abm.v92i5.9682
Descripción
Sumario:AIM: Evaluate impact of lymph node ratio as prognostic factor in gastric cancer. METHODS: We studied 463 patients with gastric cancer who underwent curative gastric surgery with D1 or D2 lymphadenectomy, Data were collected from May 1996 through December 2010 at Department of General Surgery of Parma University Hospital. We divided patients in two groups according to number of nodes removed. RESULTS: The results of the present nonrandomized retrospective single center study confirm the promising role of the LNR as an indipendent prognostic factor. Overall survival between LNR categories are statistically significant different between LNR0 and LNR1. CONCLUSION: The ratio between the number of metastatic and analyzed lymph nodes in patients with gastric cancer can discriminate patients better than the AJCC/UICC staging system: it seems to be related to a more sensitive in the evaluation of overall survival. (www.actabiomedica.it)

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