The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer

AIM: Evaluate impact of lymph node ratio as prognostic factor in gastric cancer. METHODS: We studied 463 patients with gastric cancer who underwent curative gastric surgery with D1 or D2 lymphadenectomy, Data were collected from May 1996 through December 2010 at Department of General Surgery of Parm...

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Detalles Bibliográficos
Autores principales: Giuffrida, Mario, Viani, Lorenzo, Iapichino, Gioacchino Giovanni, Cozzani, Federico, Dell’Abate, Paolo, Del Rio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689297/
https://www.ncbi.nlm.nih.gov/pubmed/34738601
http://dx.doi.org/10.23750/abm.v92i5.9682
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author Giuffrida, Mario
Viani, Lorenzo
Iapichino, Gioacchino Giovanni
Cozzani, Federico
Dell’Abate, Paolo
Del Rio, Paolo
author_facet Giuffrida, Mario
Viani, Lorenzo
Iapichino, Gioacchino Giovanni
Cozzani, Federico
Dell’Abate, Paolo
Del Rio, Paolo
author_sort Giuffrida, Mario
collection PubMed
description AIM: Evaluate impact of lymph node ratio as prognostic factor in gastric cancer. METHODS: We studied 463 patients with gastric cancer who underwent curative gastric surgery with D1 or D2 lymphadenectomy, Data were collected from May 1996 through December 2010 at Department of General Surgery of Parma University Hospital. We divided patients in two groups according to number of nodes removed. RESULTS: The results of the present nonrandomized retrospective single center study confirm the promising role of the LNR as an indipendent prognostic factor. Overall survival between LNR categories are statistically significant different between LNR0 and LNR1. CONCLUSION: The ratio between the number of metastatic and analyzed lymph nodes in patients with gastric cancer can discriminate patients better than the AJCC/UICC staging system: it seems to be related to a more sensitive in the evaluation of overall survival. (www.actabiomedica.it)
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spelling pubmed-86892972022-01-06 The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer Giuffrida, Mario Viani, Lorenzo Iapichino, Gioacchino Giovanni Cozzani, Federico Dell’Abate, Paolo Del Rio, Paolo Acta Biomed Original Article AIM: Evaluate impact of lymph node ratio as prognostic factor in gastric cancer. METHODS: We studied 463 patients with gastric cancer who underwent curative gastric surgery with D1 or D2 lymphadenectomy, Data were collected from May 1996 through December 2010 at Department of General Surgery of Parma University Hospital. We divided patients in two groups according to number of nodes removed. RESULTS: The results of the present nonrandomized retrospective single center study confirm the promising role of the LNR as an indipendent prognostic factor. Overall survival between LNR categories are statistically significant different between LNR0 and LNR1. CONCLUSION: The ratio between the number of metastatic and analyzed lymph nodes in patients with gastric cancer can discriminate patients better than the AJCC/UICC staging system: it seems to be related to a more sensitive in the evaluation of overall survival. (www.actabiomedica.it) Mattioli 1885 2021 2021-11-03 /pmc/articles/PMC8689297/ /pubmed/34738601 http://dx.doi.org/10.23750/abm.v92i5.9682 Text en Copyright: © 2021 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Original Article
Giuffrida, Mario
Viani, Lorenzo
Iapichino, Gioacchino Giovanni
Cozzani, Federico
Dell’Abate, Paolo
Del Rio, Paolo
The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title_full The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title_fullStr The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title_full_unstemmed The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title_short The metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
title_sort metastatic lymph node ratio is a better prognostic factor than the number of metastatic limph node after curative resection for gastric cancer
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689297/
https://www.ncbi.nlm.nih.gov/pubmed/34738601
http://dx.doi.org/10.23750/abm.v92i5.9682
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