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Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site

Protein dynamics governs most of the fundamental processes in the human body. Particularly, the dynamics of loops located near an active site can be involved in the positioning of the substrate and the reaction mechanism. The understanding of the functioning of dynamic loops is therefore a challenge...

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Detalles Bibliográficos
Autores principales: Mirgaux, Manon, Leherte, Laurence, Wouters, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689440/
https://www.ncbi.nlm.nih.gov/pubmed/34949925
http://dx.doi.org/10.1177/11786469211052964

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