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Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial

OBJECTIVE: Heart failure (HF) is a common and highly morbid cardiovascular disorder. Oxidative stress worsens HF, and uric acid (UA) is a useful oxidative stress marker. The novel anti-hyperuricemic drug febuxostat is a potent non-purine selective xanthine oxidase inhibitor. The present study examin...

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Detalles Bibliográficos
Autores principales: Suzuki, Satoshi, Yoshihisa, Akiomi, Yokokawa, Tetsuro, Kobayashi, Atsushi, Yamaki, Takayoshi, Kunii, Hiroyuki, Nakazato, Kazuhiko, Tsuda, Akihiro, Tsuda, Tatsunori, Ishibashi, Toshiyuki, Konno, Ichiro, Yamaguchi, Osamu, Machii, Hirofumi, Nozaki, Naoki, Niizeki, Takeshi, Miyamoto, Takuya, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689623/
https://www.ncbi.nlm.nih.gov/pubmed/34914568
http://dx.doi.org/10.1177/03000605211062770