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Bhlhe40 function in activated B and T(FH) cells restrains the GC reaction and prevents lymphomagenesis
The generation of high-affinity antibodies against pathogens and vaccines requires the germinal center (GC) reaction, which relies on a complex interplay between specialized effector B and CD4 T lymphocytes, the GC B cells and T follicular helper (T(FH)) cells. Intriguingly, several positive key reg...
Autores principales: | Rauschmeier, René, Reinhardt, Annika, Gustafsson, Charlotte, Glaros, Vassilis, Artemov, Artem V., Dunst, Josefine, Taneja, Reshma, Adameyko, Igor, Månsson, Robert, Busslinger, Meinrad, Kreslavsky, Taras |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689665/ https://www.ncbi.nlm.nih.gov/pubmed/34919144 http://dx.doi.org/10.1084/jem.20211406 |
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