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SARS-CoV-2 Interference of Influenza Virus Replication in Syrian Hamsters

In hamsters, SARS-CoV-2 infection at the same time as or before H3N2 influenza virus infection resulted in significantly reduced influenza virus titers in the lungs and nasal turbinates. This interference may be correlated with SARS-CoV-2–induced expression of MX1.

Detalles Bibliográficos
Autores principales: Halfmann, Peter J, Nakajima, Noriko, Sato, Yuko, Takahashi, Kenta, Accola, Molly, Chiba, Shiho, Fan, Shufang, Neumann, Gabriele, Rehrauer, William, Suzuki, Tadaki, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689717/
https://www.ncbi.nlm.nih.gov/pubmed/34875072
http://dx.doi.org/10.1093/infdis/jiab587
Descripción
Sumario:In hamsters, SARS-CoV-2 infection at the same time as or before H3N2 influenza virus infection resulted in significantly reduced influenza virus titers in the lungs and nasal turbinates. This interference may be correlated with SARS-CoV-2–induced expression of MX1.