Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study

Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination, people living with human immunodeficiency virus (HIV, PLWH) had lower surrogate virus neutralization test response (P = .03) and a trend toward lower immunoglobulin G (IgG) response (P = .08), particularly among...

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Autores principales: Spinelli, Matthew A, Peluso, Michael J, Lynch, Kara L, Yun, Cassandra, Glidden, David V, Henrich, Timothy J, Deeks, Steven G, Gandhi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689738/
https://www.ncbi.nlm.nih.gov/pubmed/34864962
http://dx.doi.org/10.1093/cid/ciab1009
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author Spinelli, Matthew A
Peluso, Michael J
Lynch, Kara L
Yun, Cassandra
Glidden, David V
Henrich, Timothy J
Deeks, Steven G
Gandhi, Monica
author_facet Spinelli, Matthew A
Peluso, Michael J
Lynch, Kara L
Yun, Cassandra
Glidden, David V
Henrich, Timothy J
Deeks, Steven G
Gandhi, Monica
author_sort Spinelli, Matthew A
collection PubMed
description Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination, people living with human immunodeficiency virus (HIV, PLWH) had lower surrogate virus neutralization test response (P = .03) and a trend toward lower immunoglobulin G (IgG) response (P = .08), particularly among those with lower CD4(+) T-cell counts and who received the BNT162b2 vaccine. Study of the impact of supplemental vaccine doses among PLWH is needed.
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spelling pubmed-86897382022-01-05 Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study Spinelli, Matthew A Peluso, Michael J Lynch, Kara L Yun, Cassandra Glidden, David V Henrich, Timothy J Deeks, Steven G Gandhi, Monica Clin Infect Dis Brief Report Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination, people living with human immunodeficiency virus (HIV, PLWH) had lower surrogate virus neutralization test response (P = .03) and a trend toward lower immunoglobulin G (IgG) response (P = .08), particularly among those with lower CD4(+) T-cell counts and who received the BNT162b2 vaccine. Study of the impact of supplemental vaccine doses among PLWH is needed. Oxford University Press 2021-12-05 /pmc/articles/PMC8689738/ /pubmed/34864962 http://dx.doi.org/10.1093/cid/ciab1009 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_modelThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
spellingShingle Brief Report
Spinelli, Matthew A
Peluso, Michael J
Lynch, Kara L
Yun, Cassandra
Glidden, David V
Henrich, Timothy J
Deeks, Steven G
Gandhi, Monica
Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title_full Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title_fullStr Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title_full_unstemmed Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title_short Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study
title_sort differences in post-mrna vaccination severe acute respiratory syndrome coronavirus 2 (sars-cov-2) immunoglobulin g (igg) concentrations and surrogate virus neutralization test response by human immunodeficiency virus (hiv) status and type of vaccine: a matched case-control observational study
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689738/
https://www.ncbi.nlm.nih.gov/pubmed/34864962
http://dx.doi.org/10.1093/cid/ciab1009
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