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The tryptophan pathway and nicotinamide supplementation in ischaemic acute kidney injury

BACKGROUND: Down-regulation of the enzymes involved in tryptophan-derived nicotinamide (NAM) adenine dinucleotide (NAD(+)) production was identified after acute kidney injury (AKI), leading to the hypothesis that supplementation with NAM may increase the kidney NAD(+) content, rescuing tryptophan pa...

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Detalles Bibliográficos
Autores principales: Piedrafita, Alexis, Balayssac, Stéphane, Mayeur, Nicolas, Gazut, Stéphane, Grossac, Julia, Buleon, Marie, Alves, Melinda, Klein, Julie, Minville, Vincent, Marcheix, Bertrand, Schanstra, Joost P, Faguer, Stanislas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690092/
https://www.ncbi.nlm.nih.gov/pubmed/34950461
http://dx.doi.org/10.1093/ckj/sfab050