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Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes

Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperatur...

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Detalles Bibliográficos
Autores principales: Begum, Zubeda, Sannabe, Haruka, Seki, Chigusa, Okuyama, Yuko, Kwon, Eunsang, Uwai, Koji, Tokiwa, Michio, Tokiwa, Suguru, Takeshita, Mitsuhiro, Nakano, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690173/
https://www.ncbi.nlm.nih.gov/pubmed/35423042
http://dx.doi.org/10.1039/d0ra09041g
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author Begum, Zubeda
Sannabe, Haruka
Seki, Chigusa
Okuyama, Yuko
Kwon, Eunsang
Uwai, Koji
Tokiwa, Michio
Tokiwa, Suguru
Takeshita, Mitsuhiro
Nakano, Hiroto
author_facet Begum, Zubeda
Sannabe, Haruka
Seki, Chigusa
Okuyama, Yuko
Kwon, Eunsang
Uwai, Koji
Tokiwa, Michio
Tokiwa, Suguru
Takeshita, Mitsuhiro
Nakano, Hiroto
author_sort Begum, Zubeda
collection PubMed
description Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature.
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spelling pubmed-86901732022-04-13 Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes Begum, Zubeda Sannabe, Haruka Seki, Chigusa Okuyama, Yuko Kwon, Eunsang Uwai, Koji Tokiwa, Michio Tokiwa, Suguru Takeshita, Mitsuhiro Nakano, Hiroto RSC Adv Chemistry Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature. The Royal Society of Chemistry 2020-12-22 /pmc/articles/PMC8690173/ /pubmed/35423042 http://dx.doi.org/10.1039/d0ra09041g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Begum, Zubeda
Sannabe, Haruka
Seki, Chigusa
Okuyama, Yuko
Kwon, Eunsang
Uwai, Koji
Tokiwa, Michio
Tokiwa, Suguru
Takeshita, Mitsuhiro
Nakano, Hiroto
Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title_full Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title_fullStr Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title_full_unstemmed Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title_short Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes
title_sort simple primary β-amino alcohols as organocatalysts for the asymmetric michael addition of β-keto esters to nitroalkenes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690173/
https://www.ncbi.nlm.nih.gov/pubmed/35423042
http://dx.doi.org/10.1039/d0ra09041g
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