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Computational identification of potential chemoprophylactic agents according to dynamic behavior of peroxisome proliferator-activated receptor gamma

Peroxisome proliferator-activated receptor gamma (PPAR(γ)) is an attractive target for chemoprevention of lung carcinoma, however its highly dynamic nature has plagued drug development for decades, with difficulties in receptor modeling for structure-based design. In this work, an integrated recepto...

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Detalles Bibliográficos
Autores principales:	Yang, Zhiwei, Zhao, Yizhen, Hao, Dongxiao, Wang, He, Li, Shengqing, Jia, Lintao, Yuan, Xiaohui, Zhang, Lei, Meng, Lingjie, Zhang, Shengli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690233/ https://www.ncbi.nlm.nih.gov/pubmed/35423024 http://dx.doi.org/10.1039/d0ra09059j

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