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Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody

BACKGROUND: Cyclin-dependent kinase 4 (CDK4) when hyperactivated drives development and maintenance of most tumour types, thus prompting its use as an essential cancer treatment target and a diagnostic tool. Target-binding molecules, such as single-chain variable fragment (scFv) antibodies, hold tre...

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Detalles Bibliográficos
Autores principales:	Zhao, Jialiang, Xu, Jingjing, Yang, Tianbin, Yu, Xinze, Cheng, Cheng, Zhang, Tong, Ren, Ze, Li, Na, Yang, Fang, Li, Guiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690526/ https://www.ncbi.nlm.nih.gov/pubmed/34930213 http://dx.doi.org/10.1186/s12896-021-00729-z

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