HIF-1α switches the functionality of TGF-β signaling via changing the partners of smads to drive glucose metabolic reprogramming in non-small cell lung cancer

BACKGROUND: Most cancer cells have fundamentally different metabolic characteristics, particularly much higher glycolysis rates than normal tissues, which support the increased demand for biosynthesis and promote tumor progression. We found that transforming growth factor (TGF)-β plays a dual functi...

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Detalles Bibliográficos
Autores principales: Huang, Yiwei, Chen, Zhencong, Lu, Tao, Bi, Guoshu, Li, Ming, Liang, Jiaqi, Hu, Zhengyang, Zheng, Yuansheng, Yin, Jiacheng, Xi, Junjie, Lin, Zongwu, Zhan, Cheng, Jiang, Wei, Wang, Qun, Tan, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690885/
https://www.ncbi.nlm.nih.gov/pubmed/34930376
http://dx.doi.org/10.1186/s13046-021-02188-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690885/
https://www.ncbi.nlm.nih.gov/pubmed/34930376
http://dx.doi.org/10.1186/s13046-021-02188-y

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