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Mammalian Ssu72 phosphatase preferentially considers tissue-specific actively transcribed gene expression by regulating RNA Pol II transcription

Reversible phosphorylation of the C-terminal domain (CTD) of RNA polymerase II (Pol II) is essential for gene expression control. How altering the phosphorylation of the CTD contributes to gene expression in mammalian systems remains poorly understood. Methods: Primary mouse embryonic fibroblasts, h...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Soo, Jeon, Yoon, Jang, Yoon Ok, Lee, Ho, Shin, Yong, Lee, Chang-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690912/
https://www.ncbi.nlm.nih.gov/pubmed/34987641
http://dx.doi.org/10.7150/thno.62274