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Mammalian Ssu72 phosphatase preferentially considers tissue-specific actively transcribed gene expression by regulating RNA Pol II transcription
Reversible phosphorylation of the C-terminal domain (CTD) of RNA polymerase II (Pol II) is essential for gene expression control. How altering the phosphorylation of the CTD contributes to gene expression in mammalian systems remains poorly understood. Methods: Primary mouse embryonic fibroblasts, h...
Autores principales: | Kim, Hyun-Soo, Jeon, Yoon, Jang, Yoon Ok, Lee, Ho, Shin, Yong, Lee, Chang-Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690912/ https://www.ncbi.nlm.nih.gov/pubmed/34987641 http://dx.doi.org/10.7150/thno.62274 |
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