Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma

Rationale: Despite evidence suggesting that the tumor microenvironment (TME) in malignant pleural mesothelioma (MPM) is linked with poor prognosis, there is a lack of studies that functionally characterize stromal cells and tumor-infiltrating lymphocytes (TILs). Here, we aim to characterize the stro...

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Detalles Bibliográficos
Autores principales: Yang, Haitang, Berezowska, Sabina, Dorn, Patrick, Zens, Philipp, Chen, Peiru, Peng, Ren-Wang, Marti, Thomas M., Kocher, Gregor J, Schmid, Ralph A., Hall, Sean R.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690914/
https://www.ncbi.nlm.nih.gov/pubmed/34987640
http://dx.doi.org/10.7150/thno.61209

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