Tubular epithelial cell-to-macrophage communication forms a negative feedback loop via extracellular vesicle transfer to promote renal inflammation and apoptosis in diabetic nephropathy

Background: Macrophage infiltration around lipotoxic tubular epithelial cells (TECs) is a hallmark of diabetic nephropathy (DN). However, how these two types of cells communicate remains obscure. We previously demonstrated that LRG1 was elevated in the process of kidney injury. Here, we demonstrated...

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Detalles Bibliográficos
Autores principales: Jiang, Wen-juan, Xu, Chuan-ting, Du, Chang-lin, Dong, Jia-hui, Xu, Song-bing, Hu, Bing-feng, Feng, Rui, Zang, Dan-dan, Meng, Xiao-ming, Huang, Cheng, Li, Jun, Ma, Tao-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690920/
https://www.ncbi.nlm.nih.gov/pubmed/34987648
http://dx.doi.org/10.7150/thno.63735

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