Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities

Purpose: To establish a clinically applicable genomic clustering system, we investigated the interactive landscape of driver mutations in intrahepatic cholangiocarcinoma (ICC). Methods: The genomic data of 1481 ICCs from diverse populations was analyzed to investigate the pair-wise co-occurrences or...

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Detalles Bibliográficos
Autores principales: Wang, Xiang-Yu, Zhu, Wen-Wei, Wang, Zheng, Huang, Jian-Bo, Wang, Sheng-Hao, Bai, Fu-Mao, Li, Tian-En, Zhu, Ying, Zhao, Jing, Yang, Xin, Lu, Lu, Zhang, Ju-Bo, Jia, Hu-Liang, Dong, Qiong-Zhu, Chen, Jin-Hong, Andersen, Jesper B., Ye, Dan, Qin, Lun-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690927/
https://www.ncbi.nlm.nih.gov/pubmed/34987644
http://dx.doi.org/10.7150/thno.63417

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