Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype

Rationale: Around 10%-20% patients with glioblastoma (GBM) are diagnosed with more than one tumor lesions or multifocal GBM (mGBM). However, the understanding on genetic, DNA methylomic, and transcriptomic characteristics of mGBM is still limited. Methods: In this study, we collected nine tumor foci...

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Detalles Bibliográficos
Autores principales: Lv, Sheng-Qing, Fu, Zhen, Yang, Lin, Li, Qing-Rui, Zhu, Jiang, Gai, Qu-Jing, Mao, Min, He, Jiang, Qin, Yan, Yao, Xiao-Xue, Lan, Xi, Wang, Yan-Xia, Lu, Hui-Min, Xiang, Yan, Zhang, Zuo-Xin, Huang, Guo-Hao, Yang, Wei, Kang, Ping, Sun, Zhijian, Shi, Yu, Yao, Xiao-Hong, Bian, Xiu-Wu, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690928/
https://www.ncbi.nlm.nih.gov/pubmed/34987659
http://dx.doi.org/10.7150/thno.65739

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