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Development of a unilateral ureteral obstruction model in cynomolgus monkeys

BACKGROUND: Chronic kidney disease (CKD) has a high global prevalence and large unmet need. Central to developing new CKD therapies are in vivo models in CKD. However, next‐generation antibody, protein, and gene therapies are highly specific, meaning some do not cross‐react with rodent targets. This...

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Detalles Bibliográficos
Autores principales: Huang, Linghong, Ni, Jia, Duncan, Tanika, Song, Zhizhan, Johnson, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690991/
https://www.ncbi.nlm.nih.gov/pubmed/34977487
http://dx.doi.org/10.1002/ame2.12185

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