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Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratification

BACKGROUND: Polygenic risk scores (PRS) could potentially improve breast cancer screening recommendations. Before a PRS can be considered for implementation, it needs rigorous evaluation, using performance measures that can inform about its future clinical value. OBJECTIVES: To evaluate the prognost...

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Detalles Bibliográficos
Autores principales: Olsen, Maria, Fischer, Krista, Bossuyt, Patrick M., Goetghebeur, Els
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691010/
https://www.ncbi.nlm.nih.gov/pubmed/34930164
http://dx.doi.org/10.1186/s12885-021-08937-8