Low thyroid hormone receptor alpha-2 (THRα-2) tumor expression is associated with unfavorable tumor characteristics and high breast cancer mortality

BACKGROUND: The active thyroid hormone triiodothyronine (T3) has been found to have an estrogen-like effect on breast cancer cells. Thyroid hormone receptor alpha-2 (THRα-2) acts as an antagonist for triiodothyronine (T3) signaling, and a low expression has been associated with unfavorable tumor cha...

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Detalles Bibliográficos
Autores principales: Sandsveden, Malte, Borgquist, Signe, Rosendahl, Ann H., Manjer, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691018/
https://www.ncbi.nlm.nih.gov/pubmed/34930399
http://dx.doi.org/10.1186/s13058-021-01496-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691018/
https://www.ncbi.nlm.nih.gov/pubmed/34930399
http://dx.doi.org/10.1186/s13058-021-01496-7

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