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Low thyroid hormone receptor alpha-2 (THRα-2) tumor expression is associated with unfavorable tumor characteristics and high breast cancer mortality

BACKGROUND: The active thyroid hormone triiodothyronine (T3) has been found to have an estrogen-like effect on breast cancer cells. Thyroid hormone receptor alpha-2 (THRα-2) acts as an antagonist for triiodothyronine (T3) signaling, and a low expression has been associated with unfavorable tumor cha...

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Detalles Bibliográficos
Autores principales:	Sandsveden, Malte, Borgquist, Signe, Rosendahl, Ann H., Manjer, Jonas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691018/ https://www.ncbi.nlm.nih.gov/pubmed/34930399 http://dx.doi.org/10.1186/s13058-021-01496-7

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