Cargando…

Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart–Wallach type reaction

The 3,4-dihydroquinazolinone (DHQ) moiety is a highly valued scaffold in medicinal chemistry due to the vast number of biologically-active compounds based on this core structure. Current synthetic methods to access these compounds are limited in terms of diversity and flexibility and often require t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bokale-Shivale, Suvarna, Amin, Mohammad A., Sawant, Rajiv T., Stevens, Marc Y., Turanli, Lewend, Hallberg, Adam, Waghmode, Suresh B., Odell, Luke R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691039/ https://www.ncbi.nlm.nih.gov/pubmed/35423044 http://dx.doi.org/10.1039/d0ra10142g

Ejemplares similares

Microwave-Assisted aza-Friedel–Crafts Arylation of N-Acyliminium Ions: Expedient Access to 4-Aryl 3,4-Dihydroquinazolinones
por: Sawant, Rajiv T., et al.
Publicado: (2018)

Fasciolasis, T y Leuckart
Publicado: (1986)

The Rudolph Leuckart Celebration
por: Stiles, Chas. Wardell
Publicado: (1895)

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro‐Oxindole Dihydroquinazolinones as IRAP Inhibitors
por: Engen, Karin, et al.
Publicado: (2020)

Compact quotients of Cahen-Wallach spaces
por: Kath, Ines, et al.
Publicado: (2019)

Wallach, Interpretación clínica de pruebas diagnósticas
Publicado: (2012)

Symmetry representation theory and its applications: in honor of Nolan R. Wallach
por: Howe, Roger, et al.
Publicado: (2014)

Antitubercular, Cytotoxicity, and Computational Target Validation of Dihydroquinazolinone Derivatives
por: Venugopala, Katharigatta N., et al.
Publicado: (2022)

“On-Water” Synthesis of Quinazolinones and Dihydroquinazolinones Starting from o-Bromobenzonitrile
por: Liu, Zibin, et al.
Publicado: (2018)

Synthesis, molecular docking, and cytotoxicity of quinazolinone and dihydroquinazolinone derivatives as cytotoxic agents
por: Taayoshi, Fahimeh, et al.
Publicado: (2022)

Characterization of Route Specific Impurities Found in Methamphetamine Synthesized by the Leuckart and Reductive Amination Methods
por: Kunalan, Vanitha, et al.
Publicado: (2009)

Gold(iii) promoted formation of dihydroquinazolinones: double X–H activation by gold
por: Kadiyala, Veerabhushanam, et al.
Publicado: (2020)

Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
por: Venkateshwarlu, Rapolu, et al.
Publicado: (2020)

Exploiting racemism enhanced organic room-temperature phosphorescence to demonstrate Wallach’s rule in the lighting chiral chromophores
por: Wu, Xiugang, et al.
Publicado: (2020)

Archigetes Leuckart, 1878 (Cestoda, Caryophyllidea): diversity of enigmatic fish tapeworms with monoxenic life cycles
por: Uhrovič, Dalibor, et al.
Publicado: (2022)

Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4
por: Ashton, Trent D., et al.
Publicado: (2023)

Origin, differentiation and functional ultrastructure of egg envelopes in the cestode Echinococcus multilocularis Leuckart, 1863 (Cyclophyllidea: Taeniidae)
por: Świderski, Zdzisław, et al.
Publicado: (2017)

Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
por: Murthy, V. Narayana, et al.
Publicado: (2018)

Direct manipulation of perceived angular declination affects perceived size and distance: a replication and extension of Wallach and O’Leary (1982)
por: Williams, Morgan J. C., et al.
Publicado: (2015)

Three new species of Thelepus Leuckart, 1849 from Europe and a re-description of T. cincinnatus (Fabricius, 1780) (Annelida, Terebellidae)
por: Jirkov, Igor
Publicado: (2018)

Dihydroquinazolinones as adaptative C(sp(3)) handles in arylations and alkylations via dual catalytic C–C bond-functionalization
por: Lv, Xin-Yang, et al.
Publicado: (2022)

A new view on the morphology and phylogeny of eugregarines suggested by the evidence from the gregarine Ancora sagittata (Leuckart, 1860) Labbé, 1899 (Apicomplexa: Eugregarinida)
por: Simdyanov, Timur G., et al.
Publicado: (2017)

High acidity cellulose sulfuric acid from sulfur trioxide: a highly efficient catalyst for the one step synthesis of xanthene and dihydroquinazolinone derivatives
por: Yue, Xiaofei, et al.
Publicado: (2019)

Studies on Pd/NiFe(2)O(4) catalyzed ligand-free Suzuki reaction in aqueous phase: synthesis of biaryls, terphenyls and polyaryls
por: Borhade, Sanjay R, et al.
Publicado: (2011)

Fear From Afar, Not So Risky After All: Distancing Moderates the Relationship Between Fear and Risk Taking
por: Mayiwar, Lewend, et al.
Publicado: (2021)

Generation of (34)S-substituted protein-bound [4Fe-4S] clusters using (34)S-L-cysteine
por: Crack, Jason C, et al.
Publicado: (2019)

Synthesis and in vitro antiviral evaluation of 4-substituted 3,4-dihydropyrimidinones
por: Kumarasamy, Dhanabal, et al.
Publicado: (2017)

34th Symposium on Planetary Nebulae
por: Osterbrock, D, et al.
Publicado: (1968)

Surface Nanostructuration and Wettability of Electrodeposited Poly(3,4-ethylenedioxypyrrole) and Poly(3,4-propylenedioxypyrrole) Films Substituted by Aromatic Groups
por: Diouf, Djibril, et al.
Publicado: (2018)

Synthesis and Energetic Properties of N-Substituted 3,4- and 3,5-Dinitropyrazoles
por: Kuehl, Valerie A., et al.
Publicado: (2023)

Nanobiotechnology and blood substitutes
por: Saini, Rajiv, et al.
Publicado: (2011)

Exploring the Anti-Cancer Mechanism of Novel 3,4′-Substituted Diaryl Guanidinium Derivatives
por: Previtali, Viola, et al.
Publicado: (2020)

Design and Synthesis of N-Substituted 3,4-Pyrroledicarboximides as Potential Anti-Inflammatory Agents
por: Redzicka, Aleksandra, et al.
Publicado: (2021)

Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with In Vitro Growth Inhibitory and In Vivo Antitumor Activity
por: Turanlı, Sümeyye, et al.
Publicado: (2022)

Opioid Addiction/Pregnancy and Neonatal Abstinence Syndrome (NAS): A Preliminary Open-Label Study of Buprenorphine Maintenance and Drug Use Targeted Psychotherapy (DUST) on Cessation of Addictive Drug Use
por: Tabi, Sarah, et al.
Publicado: (2020)

Facile Preparation of the Tosylhydrazone Derivatives of a Series of Racemic trans-3,4-Substituted Cyclopentanones
por: Bouhadir, Kamal H., et al.
Publicado: (2011)

Access and modulation of substituted 1-methyl-1,6-dihydropyrazolo[3,4-c]pyrazoles
por: Ostache, Nicu-Cosmin, et al.
Publicado: (2021)

Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate
por: Harisha, Mysore Bhyrappa, et al.
Publicado: (2020)

Antinociceptive properties of new coumarin derivatives bearing substituted 3,4-dihydro-2H-benzothiazines
por: Alipour, Masoumeh, et al.
Publicado: (2014)

α-Lithiation and Electrophilic Substitution of 1,4,4-Trimethyl-3,4-dihydroquinolin-2-one
por: Sébastien, Bouclé, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_6drbssp3rgpi7gc7lf6dkmu7nt