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Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart–Wallach type reaction

The 3,4-dihydroquinazolinone (DHQ) moiety is a highly valued scaffold in medicinal chemistry due to the vast number of biologically-active compounds based on this core structure. Current synthetic methods to access these compounds are limited in terms of diversity and flexibility and often require t...

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Detalles Bibliográficos
Autores principales:	Bokale-Shivale, Suvarna, Amin, Mohammad A., Sawant, Rajiv T., Stevens, Marc Y., Turanli, Lewend, Hallberg, Adam, Waghmode, Suresh B., Odell, Luke R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691039/ https://www.ncbi.nlm.nih.gov/pubmed/35423044 http://dx.doi.org/10.1039/d0ra10142g

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