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IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3

BACKGROUND: Although interferon regulatory factor 2 (IRF2) was reported to stimulate virus replication by suppressing the type I interferon signaling pathway, because cell cycle arrest was found to promote viral replication, IRF2-regulated replication fork factor (FAM111A and RFC3) might be able to...

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Detalles Bibliográficos
Autores principales: Ren, Kai, Zhu, Ya, Sun, Honggang, Li, Shilin, Duan, Xiaoqiong, Li, Shuang, Li, Yujia, Li, Bin, Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691090/
https://www.ncbi.nlm.nih.gov/pubmed/34930359
http://dx.doi.org/10.1186/s12985-021-01724-8

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