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Human plasma IgG1 repertoires are simple, unique, and dynamic

Although humans can produce billions of IgG1 variants through recombination and hypermutation, the diversity of IgG1 clones circulating in human blood plasma has largely eluded direct characterization. Here, we combined several mass-spectrometry-based approaches to reveal that the circulating IgG1 r...

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Detalles Bibliográficos
Autores principales:	Bondt, Albert, Hoek, Max, Tamara, Sem, de Graaf, Bastiaan, Peng, Weiwei, Schulte, Douwe, van Rijswijck, Danique M.H., den Boer, Maurits A., Greisch, Jean-François, Varkila, Meri R.J., Snijder, Joost, Cremer, Olaf L., Bonten, Marc J.M., Heck, Albert J.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691384/ https://www.ncbi.nlm.nih.gov/pubmed/34613904 http://dx.doi.org/10.1016/j.cels.2021.08.008

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