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Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics

[Image: see text] The angiotensin-converting enzyme II (ACE2) is a key molecular player in the regulation of vessel contraction, inflammation, and reduction of oxidative stress. In addition, ACE2 has assumed a prominent role in the fight against the COVID-19 pandemic-causing virus SARS-CoV-2, as it...

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Detalles Bibliográficos
Autores principales:	Fiorillo, Bianca, Marchianò, Silvia, Moraca, Federica, Sepe, Valentina, Carino, Adriana, Rapacciuolo, Pasquale, Biagioli, Michele, Limongelli, Vittorio, Zampella, Angela, Catalanotti, Bruno, Fiorucci, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691454/ https://www.ncbi.nlm.nih.gov/pubmed/34914393 http://dx.doi.org/10.1021/acs.jcim.1c01126

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