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Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways

Toll like receptor (TLR)s have a central role in regulating innate immunity and their activation have been highlighted in the pathogenesis of rheumatoid arthritis (RA). EFL2, one of diterpenoids derived from Euphorbia seeds, is nearly unknown expect for its improving effect on acute lung injury. Our...

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Detalles Bibliográficos
Autores principales:	Tang, Jing, Cheng, Xiaolan, Yi, Shiyu, Zhang, Yuanyuan, Tang, Zhigang, Zhong, Yutong, Zhang, Qiuping, Pan, Bin, Luo, Yubin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691750/ https://www.ncbi.nlm.nih.gov/pubmed/34950033 http://dx.doi.org/10.3389/fphar.2021.773592

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