The Identification of a Novel Calcium-Dependent Link Between NAD(+) and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress

The modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) is associated with the regulation of numerous cellular processes. Despite the importance of O-GlcNAc in mediating cellular function our understanding of the mechanisms that regulate O-GlcNAc levels is limited. One factor known...

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Detalles Bibliográficos
Autores principales: Zou, Luyun, Collins, Helen E., Young, Martin E., Zhang, Jianhua, Wende, Adam R., Darley-Usmar, Victor M., Chatham, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691773/
https://www.ncbi.nlm.nih.gov/pubmed/34950703
http://dx.doi.org/10.3389/fmolb.2021.780865

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