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Improved privacy preserving method for periodical SRS publishing

Spontaneous reporting systems (SRSs) are used to collect adverse drug events (ADEs) for their evaluation and analysis. Periodical SRS data publication gives rise to a problem where sensitive, private data can be discovered through various attacks. The existing SRS data publishing methods are vulnera...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Yi, Tong, Zhu, Haibin, Shang, Wenqian, Lin, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691852/
https://www.ncbi.nlm.nih.gov/pubmed/33886662
http://dx.doi.org/10.1371/journal.pone.0250457
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author Huang, Wei
Yi, Tong
Zhu, Haibin
Shang, Wenqian
Lin, Weiguo
author_facet Huang, Wei
Yi, Tong
Zhu, Haibin
Shang, Wenqian
Lin, Weiguo
author_sort Huang, Wei
collection PubMed
description Spontaneous reporting systems (SRSs) are used to collect adverse drug events (ADEs) for their evaluation and analysis. Periodical SRS data publication gives rise to a problem where sensitive, private data can be discovered through various attacks. The existing SRS data publishing methods are vulnerable to Medicine Discontinuation Attack(MD-attack) and Substantial symptoms-attack(SS-attack). To remedy this problem, an improved periodical SRS data publishing—PPMS(k, θ, ɑ)-bounding is proposed. This new method can recognize MD-attack by ensuring that each equivalence group contains at least k new medicine discontinuation records. The SS-attack can be thwarted using a heuristic algorithm. Theoretical analysis indicates that PPMS(k, θ, ɑ)-bounding can thwart the above-mentioned attacks. The experimental results also demonstrate that PPMS(k, θ, ɑ)-bounding can provide much better protection for privacy than the existing method and the new method dose not increase the information loss. PPMS(k, θ, ɑ)-bounding can improve the privacy, guaranteeing the information usability of the released tables.
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spelling pubmed-86918522021-12-22 Improved privacy preserving method for periodical SRS publishing Huang, Wei Yi, Tong Zhu, Haibin Shang, Wenqian Lin, Weiguo PLoS One Research Article Spontaneous reporting systems (SRSs) are used to collect adverse drug events (ADEs) for their evaluation and analysis. Periodical SRS data publication gives rise to a problem where sensitive, private data can be discovered through various attacks. The existing SRS data publishing methods are vulnerable to Medicine Discontinuation Attack(MD-attack) and Substantial symptoms-attack(SS-attack). To remedy this problem, an improved periodical SRS data publishing—PPMS(k, θ, ɑ)-bounding is proposed. This new method can recognize MD-attack by ensuring that each equivalence group contains at least k new medicine discontinuation records. The SS-attack can be thwarted using a heuristic algorithm. Theoretical analysis indicates that PPMS(k, θ, ɑ)-bounding can thwart the above-mentioned attacks. The experimental results also demonstrate that PPMS(k, θ, ɑ)-bounding can provide much better protection for privacy than the existing method and the new method dose not increase the information loss. PPMS(k, θ, ɑ)-bounding can improve the privacy, guaranteeing the information usability of the released tables. Public Library of Science 2021-04-22 /pmc/articles/PMC8691852/ /pubmed/33886662 http://dx.doi.org/10.1371/journal.pone.0250457 Text en © 2021 Huang et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Huang, Wei
Yi, Tong
Zhu, Haibin
Shang, Wenqian
Lin, Weiguo
Improved privacy preserving method for periodical SRS publishing
title Improved privacy preserving method for periodical SRS publishing
title_full Improved privacy preserving method for periodical SRS publishing
title_fullStr Improved privacy preserving method for periodical SRS publishing
title_full_unstemmed Improved privacy preserving method for periodical SRS publishing
title_short Improved privacy preserving method for periodical SRS publishing
title_sort improved privacy preserving method for periodical srs publishing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691852/
https://www.ncbi.nlm.nih.gov/pubmed/33886662
http://dx.doi.org/10.1371/journal.pone.0250457
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