Directly Reprogrammed Human Neurons to Understand Age-Related Energy Metabolism Impairment and Mitochondrial Dysfunction in Healthy Aging and Neurodegeneration

Brain aging is characterized by several molecular and cellular changes grouped as the hallmarks or pillars of aging, including organelle dysfunction, metabolic and nutrition-sensor changes, stem cell attrition, and macromolecular damages. Separately and collectively, these features degrade the most...

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Detalles Bibliográficos
Autores principales: Gudenschwager, Camila, Chavez, Isadora, Cardenas, Cesar, Gonzalez-Billault, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691983/
https://www.ncbi.nlm.nih.gov/pubmed/34950417
http://dx.doi.org/10.1155/2021/5586052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691983/
https://www.ncbi.nlm.nih.gov/pubmed/34950417
http://dx.doi.org/10.1155/2021/5586052

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