Early Toll-like receptor 4 inhibition improves immune dysfunction in the hippocampus after hypoxic-ischemic brain damage

Background: Toll-like receptor 4 (TLR4) is implicated in neonatal hypoxic-ischemic brain damage (HIBD), but the underlying mechanism is unclear. Hypothesis: We hypothesized that TLR4 mediates brain damage after hypoxic ischemia (HI) by inducing abnormal neuroimmune responses, including activation of...

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Detalles Bibliográficos
Autores principales: Xing, Zhu, Zhen, Tang, Jie, Fan, Jie, Yu, Shiqi, Liu, Kaiyi, Zhu, Zhicui, OuYang, Mingyan, Hei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692118/
https://www.ncbi.nlm.nih.gov/pubmed/34975308
http://dx.doi.org/10.7150/ijms.66494

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