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Verdinexor, a Selective Inhibitor of Nuclear Exportin 1, Inhibits the Proliferation and Migration of Esophageal Cancer via XPO1/c-Myc/FOSL1 Axis

Esophageal carcinoma (EC) ranks sixth among cancers in mortality worldwide and effective drugs to reduce EC incidence and mortality are lacking. To explore potential anti-esophageal cancer drugs, we conducted drug screening and discovered that verdinexor, a selective inhibitor of nuclear exportin 1...

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Detalles Bibliográficos
Autores principales: Ou, Ling, Wang, Xinyou, Cheng, Shumin, Zhang, Min, Cui, Ruiqin, Hu, Chunxia, Liu, Shiyi, Tang, Qian, Peng, Yuying, Chai, Ruihuan, Xie, Shouxia, Wang, Shaoxiang, Huang, Wei, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692140/
https://www.ncbi.nlm.nih.gov/pubmed/34975332
http://dx.doi.org/10.7150/ijbs.66612

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