GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway

Background: G-protein-coupled receptor 43 (GPR43) is a posttranscriptional regulator involved in cholesterol metabolism. This study aimed to investigate the possible roles of GPR43 activation in podocyte lipotoxicity in diabetic nephropathy (DN) and explore the potential mechanisms. Methods: The exp...

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Detalles Bibliográficos
Autores principales: Lu, Jian, Chen, Pei Pei, Zhang, Jia Xiu, Li, Xue Qi, Wang, Gui Hua, Yuan, Ben Yin, Huang, Si Jia, Liu, Xiao Qi, Jiang, Ting Ting, Wang, Meng Ying, Liu, Wen Tao, Ruan, Xiong Zhong, Liu, Bi Cheng, Ma, Kun Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692141/
https://www.ncbi.nlm.nih.gov/pubmed/34975320
http://dx.doi.org/10.7150/ijbs.64665

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