MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is characterized by muscularized pulmonary blood vessels, leading to right heart hypertrophy and cardiac failure. However, state-of-the-art therapeutics fail to target the ongoing remodeling process. Here, this study shows that matrix metalloproteinases (MMP)-1...

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Detalles Bibliográficos
Autores principales: Chi, Pei-Ling, Cheng, Chin-Chang, Hung, Cheng-Chung, Wang, Mei-Tzu, Liu, Hsien-Yueh, Ke, Meng-Wei, Shen, Min-Ci, Lin, Kun-Chang, Kuo, Shu-Hung, Hsieh, Pin-Pen, Wann, Shue-Ren, Huang, Wei-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692144/
https://www.ncbi.nlm.nih.gov/pubmed/34975336
http://dx.doi.org/10.7150/ijbs.66472

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