Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

BACKGROUND: The neurotransmitter serotonin (5‐HT) affects valvular degeneration and dogs with myxomatous mitral valve disease (MMVD) exhibit alterations in 5‐HT signaling. In Maltese dogs, 3 single nucleotide polymorphisms (SNPs) in the 5‐HT transporter (SERT) gene are suggested to associate with MM...

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Detalles Bibliográficos
Autores principales: Reimann, Maria J., Fredholm, Merete, Cremer, Signe E., Christiansen, Liselotte B., Meurs, Kathryn M., Møller, Jacob E., Häggström, Jens, Lykkesfeldt, Jens, Olsen, Lisbeth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692205/
https://www.ncbi.nlm.nih.gov/pubmed/34599615
http://dx.doi.org/10.1111/jvim.16277

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