Cargando…

A novel air-dried multiplex high-resolution melt assay for the detection of extended-spectrum β-lactamase and carbapenemase genes

OBJECTIVES: This study aimed to develop and evaluate a novel air-dried high-resolution melt (HRM) assay to detect eight major extended-spectrum β-lactamase (ESBL) (bla(SHV) and bla(CTX-M) groups 1 and 9) and carbapenemase (bla(NDM), bla(IMP), bla(KPC), bla(VIM) and bla(OXA-48-like)) genes that confe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cubas-Atienzar, Ana I., Williams, Christopher T., Karkey, Abhilasha, Dongol, Sabina, Sulochana, Manandhar, Rajendra, Shrestha, Hobbs, Glyn, Evans, Katie, Musicha, Patrick, Feasey, Nicholas, Cuevas, Luis E., Adams, Emily R., Edwards, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692233/ https://www.ncbi.nlm.nih.gov/pubmed/34482019 http://dx.doi.org/10.1016/j.jgar.2021.08.006

Ejemplares similares

A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes
por: Manandhar, Sulochana, et al.
Publicado: (2020)

Perspectives of pharmacy employees on an inappropriate use of antimicrobials in Kathmandu, Nepal
por: Shrestha, Nistha, et al.
Publicado: (2023)

Risk factors for the development of neonatal sepsis in a neonatal intensive care unit of a tertiary care hospital of Nepal
por: Manandhar, Sulochana, et al.
Publicado: (2021)

Genomic epidemiology, antimicrobial resistance and virulence factors of Enterobacter cloacae complex causing potential community-onset bloodstream infections in a tertiary care hospital of Nepal
por: Manandhar, Sulochana, et al.
Publicado: (2022)

Speciation of common Gram-negative pathogens using a highly multiplexed high resolution melt curve assay
por: Edwards, Thomas, et al.
Publicado: (2018)

Molecular surveillance reveals widespread colonisation by carbapenemase and extended spectrum beta-lactamase producing organisms in neonatal units in Kenya and Nigeria
por: Edwards, Thomas, et al.
Publicado: (2023)

The Application of GeneXpert MTB/RIF for Smear-Negative TB Diagnosis as a Fee-Paying Service at a South Asian General Hospital
por: Shrestha, Poojan, et al.
Publicado: (2015)

Outbreaks of Serratia marcescens and Serratia rubidaea bacteremia in a central Kathmandu hospital following the 2015 earthquakes
por: Karkey, Abhilasha, et al.
Publicado: (2018)

Epidemiology, etiology, and diagnosis of health care acquired pneumonia including ventilator-associated pneumonia in Nepal
por: Dongol, Sabina, et al.
Publicado: (2021)

Very long O‐antigen chains of Salmonella Paratyphi A inhibit inflammasome activation and pyroptotic cell death
por: Mylona, Elli, et al.
Publicado: (2021)

The impact of migration and antimicrobial resistance on the transmission dynamics of typhoid fever in Kathmandu, Nepal: A mathematical modelling study
por: Saad, Neil J., et al.
Publicado: (2017)

Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal
por: Darton, Thomas C., et al.
Publicado: (2017)

Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae
por: Wilson, Hayley, et al.
Publicado: (2018)

Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type β-Lactamases
por: Stewart, Nichole K., et al.
Publicado: (2014)

Corrigendum: Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae
por: Wilson, Hayley, et al.
Publicado: (2018)

Molecular diversity of extended-spectrum β-lactamases and carbapenemases, and antimicrobial resistance
por: Sawa, Teiji, et al.
Publicado: (2020)

Emergence of β-lactamase- and carbapenemase- producing Enterobacteriaceae at integrated fish farms
por: Hamza, Dalia, et al.
Publicado: (2020)

In vitro activity of the β-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases
por: Stachyra, Thérèse, et al.
Publicado: (2009)

Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial
por: Theiss-Nyland, Katherine, et al.
Publicado: (2019)

Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal
por: Thompson, Corinne N., et al.
Publicado: (2017)

Tebipenem as an oral alternative for the treatment of typhoid caused by XDR Salmonella Typhi
por: Mylona, Elli, et al.
Publicado: (2021)

Changing Antimicrobial Resistance Trends in Kathmandu, Nepal: A 23-Year Retrospective Analysis of Bacteraemia
por: Zellweger, Raphaël M., et al.
Publicado: (2018)

Gatifloxacin versus chloramphenicol for uncomplicated enteric fever: an open-label, randomised, controlled trial
por: Arjyal, Amit, et al.
Publicado: (2011)

A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations
por: Fraser, Alice J., et al.
Publicado: (2023)

Diagnostic metabolite biomarkers of chronic typhoid carriage
por: Näsström, Elin, et al.
Publicado: (2018)

Extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae among Ethiopian children
por: Legese, Melese Hailu, et al.
Publicado: (2017)

A 23-year retrospective investigation of Salmonella Typhi and Salmonella Paratyphi isolated in a tertiary Kathmandu hospital
por: Zellweger, Raphaël M., et al.
Publicado: (2017)

Epidemiology of Extended-Spectrum Beta-Lactamase and Carbapenemase-Producing Enterobacterales in the Greater Mekong Subregion: A Systematic-Review and Meta-Analysis of Risk Factors Associated With Extended-Spectrum Beta-Lactamase and Carbapenemase Isolation
por: Singh, Shweta R., et al.
Publicado: (2021)

Direct inference and control of genetic population structure from RNA sequencing data
por: Fachrul, Muhamad, et al.
Publicado: (2023)

Multiplex PCR for Rapid Detection of Genes Encoding Class A Carbapenemases
por: Hong, Sang Sook, et al.
Publicado: (2012)

Prevalence of Acquired Carbapenemase Genes in Klebsiella Pneumoniae by Multiplex PCR in Isfahan
por: Khorvash, Farzin, et al.
Publicado: (2017)

Multiplex Real-Time PCR Assay for Six Major Carbapenemase Genes
por: Yoshioka, Nori, et al.
Publicado: (2021)

Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting
por: Musicha, Patrick, et al.
Publicado: (2017)

The Novel CarbaLux Test for Carbapenemases and Carbapenem Deactivating AmpC Beta-Lactamases
por: Pfaendler, Hans Rudolf, et al.
Publicado: (2020)

QM/MM Simulations Reveal the Determinants of Carbapenemase Activity in Class A β-Lactamases
por: Chudyk, Ewa I., et al.
Publicado: (2022)

Combined Use of the Modified Hodge Test and Carbapenemase Inhibition Test for Detection of Carbapenemase-Producing Enterobacteriaceae and Metallo-β-Lactamase-Producing Pseudomonas spp.
por: Song, Wonkeun, et al.
Publicado: (2015)

Undifferentiated Febrile Illness in Kathmandu, Nepal
por: Thompson, Corinne N., et al.
Publicado: (2015)

Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi
por: Thanh Duy, Pham, et al.
Publicado: (2020)

Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever
por: Näsström, Elin, et al.
Publicado: (2014)

Comparison of two multiplex immunochromatographic assays for the rapid detection of major carbapenemases in Enterobacterales
por: Bogaerts, Pierre, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8s2udfo9lpdr5sridq0t03r50s