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Development and validation of proton track-structure model applicable to arbitrary materials

A novel transport algorithm performing proton track-structure calculations in arbitrary materials was developed. Unlike conventional algorithms, which are based on the dielectric function of the target material, our algorithm uses a total stopping power formula and single-differential cross sections...

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Autores principales: Ogawa, Tatsuhiko, Hirata, Yuho, Matsuya, Yusuke, Kai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692440/
https://www.ncbi.nlm.nih.gov/pubmed/34934066
http://dx.doi.org/10.1038/s41598-021-01822-1
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author Ogawa, Tatsuhiko
Hirata, Yuho
Matsuya, Yusuke
Kai, Takeshi
author_facet Ogawa, Tatsuhiko
Hirata, Yuho
Matsuya, Yusuke
Kai, Takeshi
author_sort Ogawa, Tatsuhiko
collection PubMed
description A novel transport algorithm performing proton track-structure calculations in arbitrary materials was developed. Unlike conventional algorithms, which are based on the dielectric function of the target material, our algorithm uses a total stopping power formula and single-differential cross sections of secondary electron production. The former was used to simulate energy dissipation of incident protons and the latter was used to consider secondary electron production. In this algorithm, the incident proton was transmitted freely in matter until the proton produced a secondary electron. The corresponding ionising energy loss was calculated as the sum of the ionisation energy and the kinetic energy of the secondary electron whereas the non-ionising energy loss was obtained by subtracting the ionising energy loss from the total stopping power. The most remarkable attribute of this model is its applicability to arbitrary materials, i.e. the model utilises the total stopping power and the single-differential cross sections for secondary electron production rather than the material-specific dielectric functions. Benchmarking of the stopping range, radial dose distribution, secondary electron energy spectra in liquid water, and lineal energy in tissue-equivalent gas, against the experimental data taken from literature agreed well. This indicated the accuracy of the present model even for materials other than liquid water. Regarding microscopic energy deposition, this model will be a robust tool for analysing the irradiation effects of cells, semiconductors and detectors.
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spelling pubmed-86924402021-12-22 Development and validation of proton track-structure model applicable to arbitrary materials Ogawa, Tatsuhiko Hirata, Yuho Matsuya, Yusuke Kai, Takeshi Sci Rep Article A novel transport algorithm performing proton track-structure calculations in arbitrary materials was developed. Unlike conventional algorithms, which are based on the dielectric function of the target material, our algorithm uses a total stopping power formula and single-differential cross sections of secondary electron production. The former was used to simulate energy dissipation of incident protons and the latter was used to consider secondary electron production. In this algorithm, the incident proton was transmitted freely in matter until the proton produced a secondary electron. The corresponding ionising energy loss was calculated as the sum of the ionisation energy and the kinetic energy of the secondary electron whereas the non-ionising energy loss was obtained by subtracting the ionising energy loss from the total stopping power. The most remarkable attribute of this model is its applicability to arbitrary materials, i.e. the model utilises the total stopping power and the single-differential cross sections for secondary electron production rather than the material-specific dielectric functions. Benchmarking of the stopping range, radial dose distribution, secondary electron energy spectra in liquid water, and lineal energy in tissue-equivalent gas, against the experimental data taken from literature agreed well. This indicated the accuracy of the present model even for materials other than liquid water. Regarding microscopic energy deposition, this model will be a robust tool for analysing the irradiation effects of cells, semiconductors and detectors. Nature Publishing Group UK 2021-12-21 /pmc/articles/PMC8692440/ /pubmed/34934066 http://dx.doi.org/10.1038/s41598-021-01822-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ogawa, Tatsuhiko
Hirata, Yuho
Matsuya, Yusuke
Kai, Takeshi
Development and validation of proton track-structure model applicable to arbitrary materials
title Development and validation of proton track-structure model applicable to arbitrary materials
title_full Development and validation of proton track-structure model applicable to arbitrary materials
title_fullStr Development and validation of proton track-structure model applicable to arbitrary materials
title_full_unstemmed Development and validation of proton track-structure model applicable to arbitrary materials
title_short Development and validation of proton track-structure model applicable to arbitrary materials
title_sort development and validation of proton track-structure model applicable to arbitrary materials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692440/
https://www.ncbi.nlm.nih.gov/pubmed/34934066
http://dx.doi.org/10.1038/s41598-021-01822-1
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