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Generation of a lung squamous cell carcinoma three-dimensional culture model with keratinizing structures

Tumor nests in lung squamous cell carcinoma (LUSC) have a hierarchical structure resembling squamous epithelium. The nests consist of basal-like cells on the periphery and layers of keratinocyte-like cells that differentiate towards the center of the nest, forming keratin pearls. Reproducing this sp...

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Detalles Bibliográficos
Autores principales:	Kawai, Shigeto, Nakano, Kiyotaka, Tamai, Keiichi, Fujii, Etsuko, Yamada, Mimori, Komoda, Hiroshi, Sakumoto, Hirofumi, Natori, Osamu, Suzuki, Masami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692465/ https://www.ncbi.nlm.nih.gov/pubmed/34934075 http://dx.doi.org/10.1038/s41598-021-03708-8

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