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Measurement and modeling of clemastine fumarate (antihistamine drug) solubility in supercritical carbon dioxide

The solubilities of clemastine fumarate in supercritical carbon dioxide (ScCO(2)) were measured for the first time at temperature (308 to 338 K) and pressure (12 to 27 MPa). The measured solubilities were reported in terms of mole faction (mol/mol total) and it had a range from 1.61 × 10(–6) to 9.41...

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Detalles Bibliográficos
Autores principales: Sodeifian, Gholamhossein, Garlapati, Chandrasekhar, Razmimanesh, Fariba, Ghanaat-Ghamsari, Marziehsadat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692556/
https://www.ncbi.nlm.nih.gov/pubmed/34934101
http://dx.doi.org/10.1038/s41598-021-03596-y