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circRNA N6-methyladenosine methylation in preeclampsia and the potential role of N6-methyladenosine-modified circPAPPA2 in trophoblast invasion

Here, we performed N6-methyladenosine (m6A) RNA sequencing to determine the circRNA m6A methylation changes in the placentas during the pathogenesis of preeclampsia (PE). We verified the expression of the circRNA circPAPPA2 using quantitative reverse transcription-PCR. An invasion assay was carried...

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Detalles Bibliográficos
Autores principales: Zhang, Yonggang, Yang, Hongling, Long, Yan, Zhang, Yipeng, Chen, Ronggui, Shi, Junzhu, Chen, Jiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692596/
https://www.ncbi.nlm.nih.gov/pubmed/34934095
http://dx.doi.org/10.1038/s41598-021-03662-5

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