Ago-RIP Sequencing Identifies New MicroRNA-449a-5p Target Genes Increasing Sorafenib Efficacy in Hepatocellular Carcinoma

BACKGROUND: Patients with hepatocellular carcinoma (HCC) have very limited treatment options. For the last fourteen years, the multi-tyrosine kinase inhibitor sorafenib has been used as standard-of-care therapeutic agent in advanced HCC. Unfortunately, drug resistance develops in many cases. Therefo...

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Detalles Bibliográficos
Autores principales: Reinkens, Thea, Stalke, Amelie, Huge, Nicole, Vajen, Beate, Eilers, Marlies, Schäffer, Vera, Dittrich-Breiholz, Oliver, Schlegelberger, Brigitte, Illig, Thomas, Skawran, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692677/
https://www.ncbi.nlm.nih.gov/pubmed/34976171
http://dx.doi.org/10.7150/jca.66016

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