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Hypermethylation of mitochondrial DNA facilitates bone metastasis of renal cell carcinoma

Kidney cancers including clear cell carcinoma (RCC) are identified with very vulnerable mitochondria DNA (mtDNA) and frequent epigenetic aberrations. Bone metastasis from RCC is prevalent and destructive. Bone marrow contains a quite hypoxic microenvironment that usually insitigate 50% of hypermethy...

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Detalles Bibliográficos
Autores principales:	Liu, Zheng, Tian, Jinhai, Peng, Fuhong, Wang, Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692697/ https://www.ncbi.nlm.nih.gov/pubmed/34976191 http://dx.doi.org/10.7150/jca.62278

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