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Dexmedetomidine Alleviates Microglia-Induced Spinal Inflammation and Hyperalgesia in Neonatal Rats by Systemic Lipopolysaccharide Exposure

Noxious stimulus and painful experience in early life can induce cognitive deficits and abnormal pain sensitivity. As a major component of the outer membrane of gram-negative bacteria, lipopolysaccharide (LPS) injection mimics clinical symptoms of bacterial infections. Spinal microglial activation a...

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Detalles Bibliográficos
Autores principales:	Wen, Wen, Gong, Xingrui, Cheung, Hoiyin, Yang, Yanyan, Cai, Meihua, Zheng, Jijian, Tong, Xiaoping, Zhang, Mazhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692868/ https://www.ncbi.nlm.nih.gov/pubmed/34955749 http://dx.doi.org/10.3389/fncel.2021.725267

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