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Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals
Cancer is a major worldwide public health issue, responsible for millions of deaths every year. Cancer cases and deaths are expected to increase rapidly with population growth, age, and lifestyle behaviors that increase cancer risk. Long-term chemotherapy results in acquired drug resistance. Traditi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692885/ https://www.ncbi.nlm.nih.gov/pubmed/34957085 http://dx.doi.org/10.3389/fbioe.2021.799806 |
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author | Jiang, Siliang Fu, Yu Zhang, Xinyang Yu, Tong Lu, Bowen Du, Juan |
author_facet | Jiang, Siliang Fu, Yu Zhang, Xinyang Yu, Tong Lu, Bowen Du, Juan |
author_sort | Jiang, Siliang |
collection | PubMed |
description | Cancer is a major worldwide public health issue, responsible for millions of deaths every year. Cancer cases and deaths are expected to increase rapidly with population growth, age, and lifestyle behaviors that increase cancer risk. Long-term chemotherapy results in acquired drug resistance. Traditional treatment methods have limitations and cannot effectively treat distal metastatic cancers. Application of nanocarriers in multi-chemotherapy must be promoted. With research progress, the shortcomings of traditional nanocarriers have gradually become evident. Carrier-free nanodrugs with desirable bioactivity have attracted considerable attention. In this review, we provide an overview of recent reports on several carrier-free nanodrug delivery systems based on phytochemicals. This review focuses on the advantages of carrier-free nanodrugs, and provides new insights for establishment of ideal cancer treatment nanosystems. |
format | Online Article Text |
id | pubmed-8692885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86928852021-12-23 Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals Jiang, Siliang Fu, Yu Zhang, Xinyang Yu, Tong Lu, Bowen Du, Juan Front Bioeng Biotechnol Bioengineering and Biotechnology Cancer is a major worldwide public health issue, responsible for millions of deaths every year. Cancer cases and deaths are expected to increase rapidly with population growth, age, and lifestyle behaviors that increase cancer risk. Long-term chemotherapy results in acquired drug resistance. Traditional treatment methods have limitations and cannot effectively treat distal metastatic cancers. Application of nanocarriers in multi-chemotherapy must be promoted. With research progress, the shortcomings of traditional nanocarriers have gradually become evident. Carrier-free nanodrugs with desirable bioactivity have attracted considerable attention. In this review, we provide an overview of recent reports on several carrier-free nanodrug delivery systems based on phytochemicals. This review focuses on the advantages of carrier-free nanodrugs, and provides new insights for establishment of ideal cancer treatment nanosystems. Frontiers Media S.A. 2021-12-08 /pmc/articles/PMC8692885/ /pubmed/34957085 http://dx.doi.org/10.3389/fbioe.2021.799806 Text en Copyright © 2021 Jiang, Fu, Zhang, Yu, Lu and Du. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Jiang, Siliang Fu, Yu Zhang, Xinyang Yu, Tong Lu, Bowen Du, Juan Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title | Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title_full | Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title_fullStr | Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title_full_unstemmed | Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title_short | Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals |
title_sort | research progress of carrier-free antitumor nanoparticles based on phytochemicals |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692885/ https://www.ncbi.nlm.nih.gov/pubmed/34957085 http://dx.doi.org/10.3389/fbioe.2021.799806 |
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