Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells

Background: Immune checkpoint inhibitors (ICIs), such as programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1), have been widely applied in clinical and scientific research. Despite their effective antitumor effects in clinical tumor therapy, most tumors are still resistant to ICI...

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Detalles Bibliográficos
Autores principales: Tu, Jingyao, Xu, Haoran, Ma, Li, Li, Chunya, Qin, Wan, Chen, Xinyi, Yi, Ming, Sun, Li, Liu, Bo, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692903/
https://www.ncbi.nlm.nih.gov/pubmed/34976211
http://dx.doi.org/10.7150/thno.65828

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