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The wettability of electron spun membranes by synovial fluid

Aseptic loosening due to periprosthetic osteolysis has been accepted as one of the leading causes of revision procedures in patients with previous joint arthroplasty. Recently, several strategies for suppression of osteolysis were proposed, mostly based on biological treatment such as mitigation of...

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Autores principales: Hrouda, Ales, Jirkovec, Radek, Hamrikova, Petra, Vanierschot, Maarten, Denis, Kathleen, Capek, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692967/
https://www.ncbi.nlm.nih.gov/pubmed/34950485
http://dx.doi.org/10.1098/rsos.210892
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author Hrouda, Ales
Jirkovec, Radek
Hamrikova, Petra
Vanierschot, Maarten
Denis, Kathleen
Capek, Lukas
author_facet Hrouda, Ales
Jirkovec, Radek
Hamrikova, Petra
Vanierschot, Maarten
Denis, Kathleen
Capek, Lukas
author_sort Hrouda, Ales
collection PubMed
description Aseptic loosening due to periprosthetic osteolysis has been accepted as one of the leading causes of revision procedures in patients with previous joint arthroplasty. Recently, several strategies for suppression of osteolysis were proposed, mostly based on biological treatment such as mitigation of chronic inflammatory reactions. However, these biological treatments do not stop the debris migration but only reduce the inflammatory reaction. To address this shortcoming, we propose the concept of ultrahigh molecular weighted polyethylene particles filtration storage by electrospun membranes. Firstly, the surface tension of synovial fluid (SF) is obtained by use of a pendant droplet. Secondly, the contact angle of the electrospun membranes wetted by two different liquids is measured to obtain the free surface energy using of the Owens–Wendt model. Additionally, the wettability of electrospun membranes by SF as a function of technology parameters is studied.
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spelling pubmed-86929672021-12-22 The wettability of electron spun membranes by synovial fluid Hrouda, Ales Jirkovec, Radek Hamrikova, Petra Vanierschot, Maarten Denis, Kathleen Capek, Lukas R Soc Open Sci Chemistry Aseptic loosening due to periprosthetic osteolysis has been accepted as one of the leading causes of revision procedures in patients with previous joint arthroplasty. Recently, several strategies for suppression of osteolysis were proposed, mostly based on biological treatment such as mitigation of chronic inflammatory reactions. However, these biological treatments do not stop the debris migration but only reduce the inflammatory reaction. To address this shortcoming, we propose the concept of ultrahigh molecular weighted polyethylene particles filtration storage by electrospun membranes. Firstly, the surface tension of synovial fluid (SF) is obtained by use of a pendant droplet. Secondly, the contact angle of the electrospun membranes wetted by two different liquids is measured to obtain the free surface energy using of the Owens–Wendt model. Additionally, the wettability of electrospun membranes by SF as a function of technology parameters is studied. The Royal Society 2021-12-22 /pmc/articles/PMC8692967/ /pubmed/34950485 http://dx.doi.org/10.1098/rsos.210892 Text en © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Chemistry
Hrouda, Ales
Jirkovec, Radek
Hamrikova, Petra
Vanierschot, Maarten
Denis, Kathleen
Capek, Lukas
The wettability of electron spun membranes by synovial fluid
title The wettability of electron spun membranes by synovial fluid
title_full The wettability of electron spun membranes by synovial fluid
title_fullStr The wettability of electron spun membranes by synovial fluid
title_full_unstemmed The wettability of electron spun membranes by synovial fluid
title_short The wettability of electron spun membranes by synovial fluid
title_sort wettability of electron spun membranes by synovial fluid
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692967/
https://www.ncbi.nlm.nih.gov/pubmed/34950485
http://dx.doi.org/10.1098/rsos.210892
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