Naive and memory CD4(+) T cell subsets can contribute to the generation of human Tfh cells

CD4(+) T follicular helper cells (Tfh) promote B cell maturation and antibody production in secondary lymphoid organs. By using an innovative culture system based on splenocyte stimulation, we studied the dynamics of naive and memory CD4(+) T cells during the generation of a Tfh cell response. We fo...

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Detalles Bibliográficos
Autores principales: Jeger-Madiot, Raphaël, Vaineau, Romain, Heredia, Maud, Tchitchek, Nicolas, Bertrand, Lisa, Pereira, Mathias, Konza, Océane, Gouritin, Bruno, Hoareau-Coudert, Bénédicte, Corneau, Aurélien, Blanc, Catherine, Savier, Eric, Buffet, Pierre, Six, Adrien, Klatzmann, David, Moris, Arnaud, Graff-Dubois, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693005/
https://www.ncbi.nlm.nih.gov/pubmed/34984326
http://dx.doi.org/10.1016/j.isci.2021.103566

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