Cargando…
THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer
Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. Radioresistance and stemness are substantial obstacles to TNBC treatment. The THO complex (THOC) is a subunit of the TRanscription–EXport complex that functions in the coupling of transcription to nascent RNA splic...
Autores principales: | Bai, Xupeng, Ni, Jie, Beretov, Julia, Wang, Shanping, Dong, Xingli, Graham, Peter, Li, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693071/ https://www.ncbi.nlm.nih.gov/pubmed/34708581 http://dx.doi.org/10.1002/advs.202102658 |
Ejemplares similares
-
Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis
por: Bai, Xupeng, et al.
Publicado: (2021) -
Knockdown THOC2 suppresses the proliferation and invasion of melanoma
por: Zhou, Xiaowei, et al.
Publicado: (2019) -
Intellectual disability associated with a homozygous missense mutation in THOC6
por: Beaulieu, Chandree L, et al.
Publicado: (2013) -
Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin
por: Cai, Shijiao, et al.
Publicado: (2020) -
The Thoc1 Encoded Ribonucleoprotein Is Required for Myeloid Progenitor Cell Homeostasis in the Adult Mouse
por: Pitzonka, Laura, et al.
Publicado: (2014)